We are delighted to present the next issue of the Internet Journal of Pediatrics and Neonatology. We have an excellent array of papers in this issue from around the world.

LoVecchio et al from the USA present their experience of overdose in children with sustained release buprion. The perennial question of which inhaler bronchodilator advice to prescribe has been tackled by DuToit et al from South Africa. Mamouri et al in Mashad City, Iran share their experience with almost 7,000 newborns and the incidence and treatment of congential dysplasia of the hip.

From Porto Allegro, Brazil Joveleviths et al have investigated the course and demographics of diarrhoea in a socially disadvantaged area. Jamil et al from Ohio, USA discuss the differences between bone marrow and stem cell autologous transplantation after ultra-high dose myeloablative therapy.

Pantanowitz and Sur from Harvard, USA and Ontario, Canada review the conditions associated with Spina Bifida, and from Israel we have a global review of the prevalence of disability in children (Merrick and Carmeli).

El Hassan et al from Mansoura, Egypt present their findings of an depth review of the trace element status in patients with marasmus.

From Ontario, Canada and Johannesburg, South Africa Sur, Nayler and Muc detail the associated abnormalities with single umbilical arteries in their experience of 15 cases.

We also have four case reports, two from the Great Britain (Govindaraj et al with a case of seizures in a 10 year old girl, and Chakrabati et al with isolated pulmonary vein stenosis mimicking chronic lung disease). From Turkey Kutlu et al present a case of VATER association with spinal cord lipoma and horseshoe kidney, and from Owo, Nigeria Oseni et al present three cases of Epidermolysis Bullosa.

Finally Mike South from Australia presents his excellent and extensive literature review.

We are proud to present papers from six continents and hope that this excellent and varied selection will stimulate further submissions.

Patrick Davies and Adam Fox

Editor in Chief, The Internet Journal of Pediatrics and Neonatology.