ISPUB.com / IJOVS/6/1/8757
  • Author/Editor Login
  • Registration
  • Facebook
  • Google Plus

ISPUB.com

Internet
Scientific
Publications

  • Home
  • Journals
  • Latest Articles
  • Disclaimers
  • Article Submissions
  • Contact
  • Help
  • The Internet Journal of Ophthalmology and Visual Science
  • Volume 6
  • Number 1

Original Article

Reliability of Cycloplegic Autorefractor Measurements to determine Spherical and Astigmatic Refractive Errors in Young Children

S Pedamallu, K Reddy, R Pedamallu, C Pedamallu

Keywords

autorefractor, cycloplegic autorefraction, non-cycloplegic autorefraction

Citation

S Pedamallu, K Reddy, R Pedamallu, C Pedamallu. Reliability of Cycloplegic Autorefractor Measurements to determine Spherical and Astigmatic Refractive Errors in Young Children. The Internet Journal of Ophthalmology and Visual Science. 2007 Volume 6 Number 1.

Abstract


Background: This paper mainly focuses on the reliability study of cycloplegic autorefractor measurements over other methods in young children.

Material and Method
In a prospective study, 200 school children aged 8 to 15 years were evaluated for refractive errors in a period of one year. Non-cycloplegic autorefraction, followed by cycloplegic conventional retinoscopy and cycloplegic autorefraction was performed. Cyclopentolate eye drops(1 %) are used for this purpose. Fundus examination was performed in all children to exclude any posterior segment pathology. Post-mydriatic assessment was performed after one week.

Results
Post-mydriatic test values are used as gold standard. There is a no significant difference between cycloplegic autorefractor spherical power, cylindrical power and axis measurements against Post mydriatic test values. The difference is statistically significant in case of non -cycloplegic autorefraction.

Conclusion
Autorefraction with cycloplegia can be substituted for the conventional cycloplegic retinoscopy for both spherical and astigmatic refractive errors in young children.

 

Note: This study was conducted by first author at Department of Ophthalmology, Rangaraya Medical College, Kakinada, India in the year 2002-2003.

Introduction

Conventional cycloplegic retinoscopy is widely used method to determine the refractive errors in patients of all age groups. Ophthalmologists and opticians in India are increasingly using Non-cycloplegic autorefractor measurements to determine refractive errors in patients of all age groups. Their reliability is questionable especially in young children.

The present study is an attempt to determine the reliability of cycloplegic automated refractor measurements as an effective substitute for conventional cycloplegic retinoscopy in young children.

Material and Methods

It is a prospective study involving 200 school children aged 8 to 15 years. They were evaluated for refractive errors over a period of one year. Visual acuity is tested using Snellen's acuity chart. Automated refraction was performed prior to the administration of cycloplegics. It is followed by cycloplegic conventional retinoscopy and cycloplegic autorefraction. 4% lignocaine topical drops were used to minimise the irritation with cyclopentolate eye drops. 1% cyclopentolate eye drops was used for the purpose. Cyclopentolate eye drops were administered at 0 minutes, after 5 minutes and after 20 minutes. The pupillary reflex and dilatation were inspected at 35 minutes from the first drop of administration. After adequate papillary dilatation (6 mm or more), cycloplegic conventional retinoscopy followed by cycloplegic autorefraction was performed.

Retinoscopy

Conventional retinoscopy was performed with the help of streak retinoscope to determine both spherical and cylindrical measurements.

Automated refraction

Canon Autorefractor R-50m was used in the study. This instrument has automatic mode (5 readings) and +/- 0.25D increments.

Procedure

The child is comfortably seated in front of the Autorefractor. Instrument is adjusted so that the pupil is concentric with the inner alignment. The operation lever is fine adjusted until a clear bright dot appears in the centre of the inner alignment.

Figure 1
Figure 1

When the bright dot is clearest in the centre alignment ring and eye is in proper focus, measurement starts automatically. After measurements are made, the standard value will be automatically calculated and displayed within brackets. The measurement in the other eye was done in the similar way. After both eyes are measured, the results were printed automatically. Autorefractor readings were taken before and after cycloplegia.

Fundus Examination

Fundus examination with direct ophthalmoscope was performed in all children to exclude any posterior segment Pathology.

Post-Mydriatic Test

After recording visual acuity in both eyes, post-mydriatic test was performed. Different spherical and cylindrical combinations were used based on retinoscopy values, to provide best possible visual acuity in both eyes separately. Finally, pinhole test is performed with these glasses on. If there is improvement in visual acuity, the whole process is repeated for best possible visual acuity. The final spherical and cylindrical values are recorded. These post-mydriatic test values are taken as gold standard.

The Data was inputted into excel sheet and analysed. The spherical and astigmatic measurements obtained by non-cycloplegic autorefraction, cycloplegic autorefraction and cycloplegic retinoscopy are compared with values of post-mydriatic test.

Results

We used Chi test to test the level of significance. Post-mydriatic test values were taken as gold standard and compared with that of cycloplegic autorefractor measurements, non-cycloplegic autorefractor measurements and conventional cycloplegic retinoscopy.

Figure 2
Table 1: Percentage of measurements in 400 eyes of spherical power by two methods that agree

In our study 70% of cycloplegic autorefraction spherical measurements agreed within ± 0.25 D of post-mydriatic test values and 97% agreed within ±0.50D

93% of Cycloplegic retinoscopy spherical power measurements agreed within ± 0.25 D of post-mydriatic test values and 98% agreed within ±0.50 D.

52% of non-cycloplegic autorefraction spherical power measurements agreed within ± 0.25 D of post-mydriatic test values and 70% within ±0.50 D.

There is a significant difference between cycloplegic autorefractor spherical power measurements and Cycloplegic retinoscopy values with in the range of ±0.25D (P<0.001), but not with in the range of ±0.50D (P= 0.8398).

There is a significant difference between non-cycloplegic autorefractor spherical power measurements and Cycloplegic retinoscopy values with in the range of ±0.25D (P<0.001) and also with in the range of ±0.50D (P<0.001).

Figure 3
Table 2: Percentage of measurements in 400 eyes of cylindrical power by two methods that agree

In our study 95% of cycloplegic autorefraction cylindrical power measurements agreed within ±0.25 D of post-mydriatic test values and 98% within ± 0.50 D.

96% of cycloplegic retinoscopy cylindrical power measurements agreed within ±0.25 D of post-mydriatic test values and 99% within ±0.50D

85% of non-cycloplegic autorefraction cylindrical power measurements agreed within ±0.25 D of post-mydriatic test values and 89% within ±0.50 D.

There is no significant difference between cycloplegic autorefractor cylindrical power measurements and Cycloplegic retinoscopy values with in the range of ±0.25D (P=0.838) and also with in the range of ±0.50D (P=0.801).

There is a significant difference between non-Cycloplegic autorefractor cylindrical power measurements and Cycloplegic retinoscopy values with in the range of ±0.25D (P=0.02) and also with in the range of ±0.50D (P=0.04).

Figure 4
Table 3: Percentage of measurements in 400 eyes of cylindrical axis by two methods that agree

In our study 95% of cycloplegic autorefraction cylindrical axis measurements agreed within ≤ 10° of post-mydriatic test values and within 20° in 98% of eyes.

73% of cycloplegic retinoscopy cylindrical axis measurements agreed within ≤ 10° of post-mydriatic test values and within 20° in 91% of eyes.

75% of non-cycloplegic autorefraction cylindrical axis measurements agreed within ≤ 10° of post-mydriatic test values and within 20° in 89% of eyes.

There is a significant difference between cycloplegic autorefractor cylindrical axis measurements and Cycloplegic retinoscopy values with in the range of ≤ 10° (P<0.001) and also with in the range of 11° to 20° (P =0.033).

There is a significant difference between non-cycloplegic auto refractor cylindrical axis measurements and post-mydriatic test values with in the range of ≤ 10° (P =0.639) and also with in the range of 11° to 20&176; (P =0.831).

Discussion

There is remarkable agreement between Cycloplegic autorefractor spherical power measurements and Cycloplegic retinoscopy with in the range of ±0.50D is comparable.

Non-cycloplegic autorefractor spherical power measurements and Cycloplegic retinoscopy with in the range of ±0.5D are not comparable.

There is remarkable agreement between Cycloplegic autorefractor cylindrical power measurements and Cycloplegic retinoscopy with in the range of ±0.25D is comparable.

Out of the all the methods used, cycloplegic autorefractor cylindrical axis measurements is the best. It is even better than cycloplegic retinoscopy with in the range of ≤ 20°.

Non-cycloplegic autorefractor cylindrical axis measurements also can be comparable with cycloplegic retinoscopy values.

There are a few published studies concluding that the most reliable measure of spherical and astigmatic refractive error was cycloplegic autorefraction followed by non-cycloplegic autorefraction and cycloplegic subjective refraction1, 2, 3, 5, 6.

Conclusion

Cycloplegic autorefraction spherical and cylindrical measurements can be substituted for conventional cycloplegic retinoscopy in young children. It is even better than conventional cycloplegic retinoscopy for cylindrical axis measurements.

The least reliable measure was non-cycloplegic auto refraction. Despite the cost of equipment, autorefraction with cycloplegia can be comparable to conventional cycloplegic retinoscopy in accuracy in children, can be run by an ophthalmic technician and therefore eliminates the ophthalmologist's examination time required for retinoscopy. Autorefraction without cycloplegia cannot substitute for the conventional cycloplegic retinoscopy in young children.

Correspondence to

Dr. Srinivas B. Pedamallu, 7, Dryclough Close, Halifax, HX30LF, England Email: pbs6vas@yahoo.com

References

1. Walline JJ, Kinney KA, Zadnik K, Mutti DO. Repeatability and validity of astigmatism measurements. J refractive surgery 1999:15:23-31.
2. El-Defrawy S, Clarke WN, Belec F, Pham B. Evaluation of a hand-held autorefractor in children younger than 6. J Pediatr Ophthalmol Strabismus. 1998 35(2): 107-109.
3. Harvey E, Miller J, Wagner L, Dobson V. Reproducibility and accuracy of measurements with a hand held autorefractor in children. Br J Ophthalmol. 1997 Nov; 81(11): 941-948.
4. Wesemann W, Dick B. Accuracy and accommodation capability of a handheld autorefractor. J Cataract Refract Surg. 2000 Jan; 26(1): 62-70.
5. Miller JM, Harvey EM, Dobson V. Visual acuity screening versus noncycloplegic autorefraction screening for astigmatism in Native American preschool children. J AAPOS. 1999 Jun; 3(3): 160-165.
6. Harvey EM, Miller JM, Dobson V, Tyszko R, Davis AL. Measurement of refractive error in Native American preschoolers: validity and reproducibility of autorefraction. Optom Vis Sci. 2000 Mar;77(3):140-149.
7. Wood MG, Mazow ML, Prager TC. Accuracy of the Nidek ARK-900 objective refractor in comparison with retinoscopy in children ages 3 to 18 years. Am J Ophthalmol. 1998 Jul; 126(1): 100-8.
8. Celebi S, Aykan U. The comparison of cyclopentolate and atropine in patients with refractive accommodative esotropia by means of retinoscopy, autorefractometry and biometric lens thickness. Acta Ophthalmol Scand. 1999 Aug; 77(4): 426-9
9. Loewen N, Barry JC. The use of cycloplegic agents. Results of a 1999 survey of German-speaking centers for pediatric ophthalmology and strabology. Strabismus. 2000 Jun;8(2): 91-99.
10. Jaeschke R, Guyatt GH, Sackett DL. Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. JAMA. 1994 Mar 2; 271(9): 703-707.
11. Williams C, Lumb R, Harvey I, Sparrow JM. Screening for refractive errors with the Topcon PR2000 Pediatric Refractometer. Invest Ophthalmol Vis Sci. 2000 Apr; 41(5): 1031-1037.
12. Cordonnier M and Dramaix M. Screening for refractive errors in children: accuracy of the hand held refractor Retinomax to screen for astigmatism. Br J Ophthalmol. 1999 February; 83(2): 157-161.
13. Cordonnier M and Dramaix M. Screening for abnormal levels of hyperopia in children: a non-cycloplegic method with a hand held refractor. Br J Ophthalmol. 1998 November; 82(11): 1260-1264.
14. Williams C, Lumb R, Harvey I, Sparrow JM. Screening for refractive errors with the Topcon PR2000 Pediatric Refractometer. Invest Ophthalmol Vis Sci. 2000 Apr; 41(5): 1031-1037.
15. C. Liang. Comparison of measurements of refractive errors between the hand-held Retinomax and on-table autorefractors in cyclopleged and noncyclopleged children. American Journal of Ophthalmology, Volume 136, Issue 6, Pages 1120-1128.

Author Information

Srinivas B. Pedamallu, M.S, MRCSEd
Huddersfield Royal Infirmary

K. Sudhakar Reddy, M.D.
Professor and Head, Department of Ophthalmology, Rangaraya medical college

Raghuveer Pedamallu, M.S.
Department of Surgery, KMC medical college

Chandra Sekhar Pedamallu, Ph.D.
Post Doctoral Sciencist, New England Biolabs Inc.

Download PDF

Your free access to ISPUB is funded by the following advertisements:

 

BACK TO TOP
  • Facebook
  • Google Plus

© 2013 Internet Scientific Publications, LLC. All rights reserved.    UBM Medica Network Privacy Policy