Welcome to this edition of the IJPN. This is the first edition with new chief editors. We hope to continue providing a journal that is diverse, topical and interesting, and we are pleased that the outgoing editors, Dr Adam Fox and Dr Patrick Davies, will remain on the editorial board.

We are keen to make the IJPN better known in the paediatric community and to foster its development into a high-quality general paediatric journal, alongside the existing better known print journals. As was previously the case, we will only publish articles that are peer-reviewed. We recognise that this is fundamental to promoting and maintaining a journal that consistently provides it's readers with papers of a reliably high standard,

Publishing an internet-only, open-access journal has many advantages. Not least of all it provides a superb platform for multimedia formats, particularly audio-visual and we would encourage all authors to capitalise on this unique feature. It also provides for rapid access to novel findings and it is environmentally friendly. Finally, it is free. Information can be distributed to a global community of paediatricians in both rich and poor nations. We are keen to publish papers with an international relevance and our submissions certainly suggest a far-reaching readership. We will continue to provide reviews of new educational material.

In this edition we are pleased to launch a new section, “Clinical Review”, in which we will present solicited articles written by experts in the field. These will particularly aim to cover controversial topics and areas of rapid advance. In the current edition, we are excited to publish a review of the recent advances in TB diagnostics: Dr Beate Kampmann's thoughtful article provides an excellent update on the role of new cytokine-based diagnostic tools, and highlights the continuing difficulty in distinguishing TB infection and disease, particularly in children with HIV.

We will also publish “Clinical Guideline Updates” which will cover hot topics in modern paediatrics from a practical viewpoint, in a user-friendly format. We hope you enjoy the new edition.