Disseminated Cornynebacterium Propinquum (CDC group ANF 3) Infection in a Patient with Reactivated Tuberculosis
D Dominquez, N Antony
D Dominquez, N Antony. Disseminated Cornynebacterium Propinquum (CDC group ANF 3) Infection in a Patient with Reactivated Tuberculosis. The Internet Journal of Infectious Diseases. 2008 Volume 7 Number 1.
We report the first case in the medical literature of disseminated
A 76 year old white male with a remote history of pulmonary tuberculosis was admitted to the hospital with chest pain and underwent a coronary artery bypass procedure. He was admitted a few weeks later in cardiorespiratory arrest. During the resuscitation the sternal wound opened and subsequently became infected with
Due to their occasionally morphologic similarity to
These patients responded well to removal of the central line and vancomycin. This patient has several interesting features. Firstly, he was only relatively immunosuppressed and despite this developed both bacteremia as well as disseminated bone marrow infection. Secondly, the presumed portal of entry was the central line as has been described in
In conclusion, this case represents an unusual infection caused by a bacterium that has only infrequently been known to cause illness in humans. The portal of entry appears to be through breaks in the skin and mucous membranes and the illness appears to result in a low grade infection which responds to antimicrobial therapy fairly rapidly.