Haematobiochemical profiles of affected cattle at arsenic prone zone in Haringhata block of Nadia District of West Bengal in India
T Rana, S Sarkar, T Mandal, S Batabyal
arsenic, biochemical changes, cattle, haematology
T Rana, S Sarkar, T Mandal, S Batabyal. Haematobiochemical profiles of affected cattle at arsenic prone zone in Haringhata block of Nadia District of West Bengal in India. The Internet Journal of Hematology. 2007 Volume 4 Number 2.
Haematology and biochemical analysis of arsenic affected cattle revealed lower level of Haemoglobin (8.300b ± 0.221 g/dl), total erythrocytic count (5.477b±0.096 X106/µl), total leucocytic count (6.025b±0.086 X106/µl), total serum protein (6.230b±0.006 g/dl) and increased levels of blood glucose (50.631b±0.673mg/dl), Aspertate aminotransaminase /AST(33.771b±0.577 IU/l, Alanine aminotransaminase/ALT(7.566b±0.108 IU/l), blood urea nitrogen/BUN (23.995b±0.736 mg/dl) and Creatinine (1.020b±0.031mg/dl) than healthy control cattle (Hb-10.800a± 0.327 g/dl, TEC-6.764a ±0.133X106/µl, TLC-6.375a ±0.106 X103/µl, TSP-6.741a ± 0.107 g/dl, BGL-47.029a ± 0.772 mg/dl, AST-28.095a ± 0.631 IU/l, ALT-6.478a ±0.178 IU/l, BUN-15.793a ±1.023 mg/dl and Creatinine -0.816a ± 0.034 mg/dl respectively).
Arsenic is one of the most toxic elements that can be found. Despite their toxic effect, inorganic arsenic bonds occur on earth naturally in small amounts. Animals are exposed to arsenic through food, water and air. Exposure may also occur through skin contact with soil or water that contains arsenic. Food is usually the largest source except in areas where drinking water is naturally contaminated with arsenic. The effects depend on the chemical form of the arsenic, the nature of the surrounding environment and their own particular biological sensitivity.Arsenic is of great environmental concern due to extensive contamination of groundwater in the Bengal delta basin with this toxin, thereby causing carcinogenic toxicity to millions of people as well as animals. Nonaghata area of Haringhata block of Nadia District of West Bengal in India is highly arsenic affected zone. The present study was undertaken to record the clinical, haematological and biochemical changes in arsenic affected cattle and to find out parameter that is affected primarily.
Materials and Methods
A total number of thirty clinical cases suspected to be suffering from arsenic toxicity with the clinical signs including depression, prostration, weight loss, weakness, dehydration, anaemia, anorexia, diarrhoea with blood, ruminal stasis, lethargy, dermatosis, reddish urine, dry dull rough, epilated hair coat, anoestrus were screened by haemato-biochemical examinations and kept as experimental (Gr.II).Ten healthy cattle from non affected zone were kept as a healthy control group (Gr. I). Blood samples were analysed for haemoglobin (Hb), total erythrocytic count (TEC), total leucocytic count (TLC)
Results and Discussion
The mean values of Haemoglobin (Hb) percentage of Gr. II and Gr.I were 8.300 ± 0.221 g/dl and 10.800 ± 0.327 g/dl respectively. Statistical analysis revealed significance difference (P<0.01) of the Hb between two groups. Low haemoglobin percentage in animals of Gr. II was indicative of anaemia and the findings was corroborated with the reports of
From the above results it can be concluded that the arsenic toxicity results in the significant haemoconcentration and ALT, AST, BUN and Creatinine estimation are most sensitive indicator assessing the liver and kidney damage.
The authors are thankful to the Dean of the faculty for providing the necessary facilities to conduct the research work.