S Berman, D Spicer
S Berman, D Spicer. Response To The Letter To The Editor: Safety And Reliability Of Lactobacillus Supplements. The Internet Journal of Alternative Medicine. 2003 Volume 1 Number 2.
January 30th, 2004
The authors responses and explanations for the points made in the letter to the editor.
The authors will address each point in the order it appears in the letter.
A point to consider in the isolation percentages is the supplier of the micro-organisms to the companies. We saw interesting trends with our larger study in which multiple products from the same company had identical contaminants and also the absence of certain bacteria, including Bifidobacteria. In addition, we noticed that products from one company also had recovery patterns similar to the products of other companies. After speaking with microbiologists from several of our product companies, it appears that many companies may be supplied by a fairly small number of suppliers.
We, the authors, agree that there is always a possibility that the numbers of a specific organism were too small to show up with the initial dilution and plating. There is also the possibility that the Bifidobacteria in a product is very fastidious and will not grow on our media despite the fact that control organisms and other Bifidobacteria were isolated. However, that raises a very important question from two clinical microbiologists. What are the chances of organisms in small number or those that have very fastidious growth requirements being able to survive HCl, peristalsis, an onslaught of pancreatic enzymes, bile and still be present to temporarily colonize either the gastro-intestinal tract or the genitourinary tract.
If you have additional questions, please contact the authors.
Sheryl Berman, PhD. Department of Basic Sciences Bastyr University Kenmore Washington USA Email: email@example.com
Diane Spicer, MS.
Department of Basic Sciences
Kenmore Washington USA