How To Do A Procedure: Bioptome-Assisted Simultaneous Delivery of Multiple Coils for Occlusion of Large Patent Ductus Arteriosus
M Krishnan
Citation
M Krishnan. How To Do A Procedure: Bioptome-Assisted Simultaneous Delivery of Multiple Coils for Occlusion of Large Patent Ductus Arteriosus. The Internet Journal of Cardiology. 2001 Volume 1 Number 2.
Abstract
Introduction
Trans-catheter occlusion of moderate to large (> 3mm) patent ductus arteriosus (PDA) is usually achieved using expensive devices. Closure of such ducti can also be attempted using detachable coils or direct delivery of free Guianturco coils which delivers single coil. This may entail multiple deployments of further coils, prolonging the procedure and fluoroscopic exposure. Moreover, delivery of free coils runs the risk of coil embolization into the pulmonary artery or aortic branches necessitating cumbersome retrieval procedure.
Bioptome-assisted simultaneous delivery of multiple coils permits safe closure of moderate to large ducti usually in a single deployment. The advantages of this method are optimal compaction of the coil mass in the ampulla of the duct with high probability of closure of the duct in single deployment, short procedure time and fluoroscopic exposure and virtual freedom from coil embolization.
Special Hardware requirements
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Cook coils: 0.038” and 0.052” of various lengths and loop diameters
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Long Balkan sheath (Cook Inc.) – 7F and 8F or larger sizes
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Short venous loader sheath: 5F or higher sizes
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3F Cardiac Bioptome
Procedure
1. Assessment of duct size:
Measurement of minimum duct diameter should be undertaken with 2D echocardiography and aortic angiography. A pigtail catheter is placed against the duct and angiography done. The minimum duct diameter is measured by frame-by-frame analysis. This is important as the duct size varies with phases of cardiac cycle. An MPA catheter may be placed across the duct before angiography so that the duct diameter may be compared with the diameter of the catheter lying across the duct. In addition to the measured diameter, the extent of dye spillage into the pulmonary artery also should be assessed. The size of the ampulla should also be assessed .This can be readily done with echocardiography in from the suprasternal view.
2. Selection of coils:
At least one coil should be of 0.052” and further coils may be either0.052 or 0.038”. One coil loop diameter should be twice the minimum duct diameter. Other coils may be of the same diameter or smaller. Different loop diameters has the advantage that the smaller loop will coil inside the larger one resulting better compaction of the coil mass and may facilitate greater chance of closure. The length of the coils should be such that about 2 to 2 1/2 loops lie in the ampulla.
3. Selection of the long sheath and the loader:
The long sheath size should be selected such that the coil assembly moves in the sheath effortlessly without resistance. For 2 coils of 0.052” a 6F sheath will suffice. For more coils of varying sizes, larger sheaths will be required. The loading sheath should be one French size less than the long sheath.
4. Coil deployment:
Sedation:
For small children, it is better to give anesthesia using ketamine. Older children are sedated using lytic cocktail or midazolam
Preparation of the bioptome-coil assembly:
The coils are extruded from the metal tube slightly at the end having the ball. The end of one coil is stretched slightly using a hemostat. Using a proline or silk suture material, the ends of the coils are tied together so that the ball of the stretched coil end sticks a little farther than the other coils. The loader is threaded on to the bioptome. The ball of the coil is caught between the jaws of the bioptome and the coils are then withdrawn from the metal tube into the loader. The grip of the jaws on to the coil is checked by pulling at the bioptome firmly.
5. Placing the long sheath across the duct:
A stiff Amplatz exchange length wire is placed deep in the descending aorta through the multipurpose catheter. The catheter is taken out and the long sheath is passed over the wire so that its tip lies in the descending aorta about 2” beyond the duct ampulla.
6. Introduction of the bioptome-coil assembly and deployment:
The assembly with the coils inside the loader is pushed into the long sheath and the loader is withdrawn. The bioptome is pushed gently so that it moves up in the long sheath smoothly. The coil mass is pushed fully out of the distal end of the long sheath such that the whole coil mass lies dangling in the descending aorta. The long sheath is slowly withdrawn well back into the PA so that PA pressures are recorded from the side arm of the sheath. The bioptome with the coils is slowly pulled back so that the coils are drawn into the ampulla and the tip held by the bioptome lies at the PA end of the duct. Gentle pulling ensures compaction of the coils in the ampulla of the duct and a short length of the coils lie in the PA. If the deployment is suboptimal, the whole coil mass can be safely retrieved into the sheath and taken out. The same combination or a fresh assembly using different sizes and no. of coils can be prepared and deployment completed (Figures 5 and 6)
A check angiogram is done after 5 minutes. If the occlusion is complete, the jaws of the bioptome are opened thus releasing the coils and completing the deployment. If there is difficulty in releasing the coils gentle torque on the bioptome without applying traction will do. The duct closure will usually be achieved in 5 minutes. If in the unlikely event of the check angiogram showing significant residual flow after 10 minutes further coil deployment of 5cm* 5mm coils should be done from the arterial approach. The bioptome is left holding the coils; the duct is crossed from the arterial route using a glide (Terumo) wire. A 5 F MPA taper-tip catheter is introduced into the PA over the wire and the wire is removed. The coil is pushed along the catheter using a 0.038” guide wire and the deployment is completed. More coils if needed can be deployed in this manner (Figure